Core messages
💡 The CRP value indicates inflammation and infections in the body.
💡 Elevated values may indicate acute or chronic diseases.
💡 A test helps to detect inflammation early and take targeted action.
What is C-reactive protein (CRP)?
The C-reactive protein (CRP) is a protein moleculethat is produced in the liver and enters the bloodstream during inflammatory processes . As a so-called “acute-phase protein” , the CRP level rises quickly when there is tissue damage or infections .
CRP supports the immune system by activating pro-inflammatory molecules and facilitating the fight against pathogens. Since the CRP level rises just a few hours after the onset of inflammation , it is a particularly sensitive and reliable marker for acute inflammatory reactions in the body.
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Reference range of the CRP value
What values are normal?
Under normal conditions, the CRP level in the blood is very low and is often barely detectable. Generally, a CRP level of less than 5 mg/L is considered unremarkable.
For a more precise assessment, a distinction is often made between slightly elevated (5–10 mg/L), moderately elevated (10–40 mg/L), and highly elevated levels (over 40 mg/L).
Tabular Overview
Under 5 mg/L: Normal range
5–10 mg/L: Possible mild inflammation
Over 10 mg/L: Possible acute inflammation or infection
Causes of elevated CRP levels
An elevated CRP level is not specific to a single disease but indicates an inflammatory response in the body. The possible causes are diverse:
- Acute infections: Bacterial infections often lead to significantly elevated CRP levels. In the case of viral infections , the level also rises, but usually less significantly.
- Chronic inflammations: Diseases such as rheumatism, arthritis , or chronic inflammatory bowel diseases (e.g., Crohn's disease or ulcerative colitis) can cause persistently elevated CRP levels.
- Injuries and surgeries: After injuries or surgical procedures, the CRP level rises as the body activates healing and responds to potential infections.
- Autoimmune diseases: In conditions such as Lupus or Multiple Sclerosis, where the immune system attacks the body's own cells, elevated CRP levels can also be detected.
- Cardiovascular diseases: Slightly elevated CRP levels (approx. 1–3 mg/L) can indicate an increased risk for cardiovascular diseases such as heart attack or stroke .
CRP: A versatile marker in diagnostics
The CRP value is often used in combination with other examinations to obtain a more comprehensive picture of the health status. An elevated CRP value alone is rarely sufficient for a diagnosis, but it serves as a supplementary markerto locate inflammation in the body or to monitor its progression. Especially in the case of chronic diseases or autoimmune diseases , the CRP value helps to control the course of the disease and to assess the effectiveness of therapies .
CRP and cardiac risk
In cardiology , the so-called hsCRP test (high-sensitivity CRP test) is used. This test measures particularly low CRP values in the range of 0.1 to 3 mg/L and can detect even minor inflammations.An elevated hsCRP level can indicate an increased risk of cardiovascular diseases , even if no typical symptoms are present. Therefore, the hsCRP test is an important tool to identify individuals who are asymptomaticbut still at risk for atherosclerosis or a heart attack .
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What's next? Next steps for your health
The CRP level is an extremely helpful parameter for early detection of inflammation and monitoring its progression. Whether for diagnosing acute infections, monitoring chronic inflammations , or as a risk marker for cardiovascular diseases – the CRP level is versatile.
Regular checks of the CRP level allow for faster detection of health issues and targeted treatment.
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FAQ: Frequently Asked Questions about Stress, Burnout, and Cortisol Levels
What is the CRP value and why is it important?
What is the CRP value and why is it important?
The CRP value (C-reactive protein) is a marker for inflammation in the body. It indicates whether there is an acute or chronic inflammation and is often used to assess the severity and cause of inflammations.
How is the CRP value measured?
How is the CRP value measured?
The CRP level is determined by a blood test. A simple blood sample is sufficient to measure the CRP level and detect possible inflammatory processes in the body.
What reference ranges are there for the CRP value?
What reference ranges are there for the CRP value?
A normal CRP level is below 5 mg/L. Values between 5 and 10 mg/L indicate a mild inflammation, while values above 10 mg/L may suggest an acute inflammation or infection. A high CRP level is often a sign of a severe inflammation.
What can elevated CRP levels mean?
What can elevated CRP levels mean?
An elevated CRP level indicates an inflammatory response in the body. Possible causes include bacterial infections, autoimmune diseases, injuries, or chronic inflammations such as arthritis. Cardiovascular diseases can also be associated with slightly elevated CRP levels.
What symptoms can indicate a high CRP level?
What symptoms can indicate a high CRP level?
Since the CRP value is only a marker for inflammation, it does not indicate any specific symptoms itself. However, symptoms of inflammation can include fever, pain, swelling, fatigue, and redness. A CRP test is often conducted to clarify the cause of these symptoms.
What is the difference between CRP and hs-CRP?
What is the difference between CRP and hs-CRP?
The hs-CRP (high-sensitivity CRP) measures very low CRP levels and is often used to assess cardiovascular risk. While the regular CRP test measures acute inflammation, the hs-CRP test indicates subtle inflammation that may be associated with a higher risk of heart disease.
What can I do to lower my CRP level?
What can I do to lower my CRP level?
A healthy lifestyle can help lower CRP levels. Regular exercise, an anti-inflammatory diet, adequate sleep, and stress management contribute to reducing inflammation. In cases of acute inflammation, treatment with medication may be necessary.
When should the CRP level be checked?
When should the CRP level be checked?
The CRP level should be checked if there is suspicion of an acute or chronic inflammation or if symptoms such as fever, joint pain, or fatigue occur. The hs-CRP level can also be helpful in assessing the risk of cardiovascular diseases.
Can medications affect the CRP level?
Can medications affect the CRP level?
Yes, some medications can affect the CRP level. Anti-inflammatory drugs, such as corticosteroids or non-steroidal anti-inflammatory drugs (NSAIDs), can lower the CRP level. Before a CRP test, the doctor should be informed about all medications being taken.
How long does it take for the CRP level to normalize after an inflammation?
How long does it take for the CRP level to normalize after an inflammation?
The CRP level usually decreases within a few days after the cause of the inflammation has been treated. However, in chronic cases, the CRP level may remain elevated for a longer period, and regular monitoring may be necessary.
