Transferrin saturation is a measure of the proportion of iron bound in the blood relative to the total capacity of transferrin. This value is important for assessing the iron status in the body. A low transferrin saturation can indicate iron deficiency, which can lead to anemia and other health problems. An adequate iron status is crucial for the normal functioning of the body, including the formation of red blood cells and the transport of oxygen in the blood. A lack of iron can lead to fatigue, weakness, and other symptoms.